EUROPEAN HOOF. CHEMICAL COMPOSITION, PHARMACOLOGICAL PROPERTIES AND MEDICAL APPLICATION

N.N. Shurevich, A.A. Markaryan

Department of Pharmacy with a course of social pharmacy Faculty of Postgraduate vocational education pharmacists MMA named after. THEM. Sechenova st. Skladochnaya, 1, building 17, Moscow, Russia, 127018 tel. +79114636467, email. mail: [email protected]

The purpose of the work was to study the chemical composition and pharmacological properties, as well as the use in medical practice of the raw material of European hoofed grass, as well as drugs based on it. The article describes some pharmacognostic features of the dried medicinal plant raw material of the European ungulate; chemical composition various parts plants, as well as the possibility of using freshly harvested and dried medicinal plant raw materials of the clefthoof in medical and homeopathic practice.

Keywords: European hoofweed, asaron.

In the list of vascular plants of the flora of the USSR, the Kirkazonaceae family - Aristolochiaceae Juss. is represented by two genera: kirkazon (Aristolochia L.) and hoofweed Asarum L. (Asiasarum F. Maer.). The coffin genus is represented by four species: European coffin - Asarum europaeum L., heterotropoid coffin - Asarum heterotropoides Fr. Schmidt, intermediate hoof - Asarum intermedium (C.A. Mey.), Siebold's hoof - Asarum Sieboldii Mig. .

European hooffoot (Asarum europaeum L., Kirkazonaceae family - Aristolochiaceae Juss) is a perennial herbaceous polycarpic plant immersed in forest floor epigeogenic plagiotropic, creeping rhizome, consisting of monocyclic monocarpic shoots that grow acrosympodially. The root system includes a rhizome with numerous thin adventitious roots, extending evenly along the entire length of the rhizome surface. They appear on each annual shoot growth in number from 1 to 16, with an average of 6-7. The length of adventitious roots is 5-50 cm, on average 10-12 cm, diameter 0.2 cm. The depth of root penetration on sod-podzolic and gray forest soils is determined mainly by the thickness of the humus horizon and is 5-10 cm; on leached chernozems under forests it can reach 50 cm. Each shoot ends with a terminal flower. The renewal bud is large, develops in the axil of the upper middle assimilating leaf, branching occurs due to smaller buds in the axils of the lower scale-like leaves. The number of lateral branches is 2-4. The rhizome includes from 5 to 15 annual shoots, their length is 2-5 cm, diameter 0.5 cm. At the base of the annual growth, 2-3 lower scale-like leaves appear, ovoid, pointed, folded along, and pubescent. Median assimilating leaves -

two, with dark green, leathery, rounded kidney-shaped, entire-edged plates, 4.7 cm long, 6.5 cm wide. The plates are covered with short appressed hairs. The venation is palmate-reticulate. The petioles are long (5-K cm), slightly curved at the base, rising along with the shoot apex, grooved at the top, pubescent with long, spaced hairs (Fig. 1). Blooms in April-May.

Rice. 1. European hoofweed (Lvagit vigoravit I.)

The flower is solitary, apical, develops on a drooping peduncle up to 1-2 cm long, located on the litter or under it. The flower is three-dimensional, has a rudimentary, underdeveloped corolla and 3 brown-brown, fleshy triangular-ovate, 7-9 mm long and 4-6 mm wide sepals, at the end with a lanceolate, inwardly curved point. On the outside, the sepals are covered with thin hairs, on the inside - thick, strong, short in the upper part of the calyx and longer in the flower tube. The sepals grow together in the bud on their sides. There are 12 stamens, arranged in 2 circles; The stamens of the outer circle are small, those of the inner circle are large. Ovary inferior, its top part slightly conical, almost flat. The fruit is a fleshy syncarpous capsule, open; cracks that appear at the base of the column. The seeds with an appendage are triangular-ovate, flattened, 3-3.5 mm long, about 2 mm wide, grayish-brown, finely wrinkled, with a wide and deep groove. The number of seeds in each ovary nest is 1-4. The seeds ripen at the end of June (which ants love). When crushed, the stems and rhizomes emit an odor reminiscent of allspice and camphor.

The raw materials of this plant are included in the pharmacopoeias of the Netherlands, Germany, Switzerland, Poland and Sweden. Based on an extract from it, the drug “E8cago1” (an expectorant) was created in Germany. Raw materials of European cleft wolf are included in the homeopathic pharmacopoeias of the USA and India. IN Russian Federation the raw material is leaves. The quality of the raw material of the coffin leaf is regulated by VFS 42-3944-00 “European coffin leaf” and includes the following numerical indicators: essential oil - not less than 0.5%; humidity - no more than 14%; total ash - no more than 16%; ash insoluble in a 10% solution of hydrochloric acid - no more than 4%; other parts of the plant - no more than 2%; browned, darkened leaves - no more than 5%; organic impurities - no more than 1%; mineral impurity - no more than 1%. Leaves of the European hoofweed include

in the composition of the domestic collection “Stopal”, the aqueous extract of which is used for conditioned reflex therapy of alcoholism.

European hooffoot (Ayaagit eigoraeum B.) is used in folk medicine as an emetic, expectorant, and has antibacterial, anti-inflammatory and antispasmodic effects. An infusion of leaves is drunk for diseases of the stomach, liver, and kidneys; decoction - for heart disease, alcoholism and poisoning poisonous mushrooms, nervous excitement, migraines, as a diuretic and for dropsy, jaundice, malaria, eczema, epilepsy. In addition, a decoction of the roots and rhizomes of the coffin is used as a diuretic for kidney diseases. A decoction of underground organs in milk is especially effective. There is evidence that a decoction of rhizomes increases the amount of male semen. To enhance sexual desire and potency, use an infusion of rhizomes in grape syrup. An aqueous infusion of the plant's raw materials is drunk for diseases of the stomach, liver, kidneys, a decoction for heart disease, alcoholism and poisoning with poisonous mushrooms (as an emetic), nervous excitement, migraines, as a diuretic for dropsy, as well as for jaundice, malaria, eczema, epilepsy . Infusions and decoctions of coffin rhizomes are used for fever, epilepsy, arthritis, kidney and liver diseases, in the treatment of silicosis, inflammation of the upper respiratory tract, stomatitis, gastritis, helminthic infestations, bleeding, tumors of various etiologies, asthma, hysteria, migraines, impotence, oligomenorrhea. Powder of rhizomes with milk is taken for diarrhea.

In Siberia, a decoction of underground organs in the form of lotions is used for headaches, and is also taken orally for dyspepsia, enteritis, jaundice and to improve digestion. Old wounds and ulcers are washed with the infusion, and lichens are lubricated. Dried and crushed rhizomes with roots are sniffed for a runny nose, headache, and deafness. Fresh and crushed hoof leaves are applied to abscesses, and their vinegar tincture is applied to the affected areas of the skin for scabies. The eyes are washed with a decoction for various eye diseases.

Herbal preparations from the rhizomes of the cleft foot exhibit emetic, expectorant, diuretic, lactogonic, antibacterial, anthelmintic, anti-inflammatory, hemostatic, antispasmodic, tonic, choleretic, laxative, antipyretic, sedative and antisclerotic effects. In the experiment, they increase the strength of capillary walls, reduce heart rate, and increase the force of myocardial contractions. The essential extract of underground organs has an emetic effect. A tincture of fresh leaves was included in the complex tincture “Akofit”, FS 42-60-72 “Fresh leaf of the European hoofed grass”, which was used externally for acute radiculitis and neuralgia. An aqueous infusion of leaves is drunk for headaches, deafness, paralysis with loss of speech, epilepsy, gout and rheumatism, nervous and heart diseases. In Hungary it is used in the treatment of spastic bronchitis. Coffin essential oil has a pleasant scent of allspice and can be used in dental practice, perfumery, and the food industry. In veterinary medicine, powder and aqueous infusion of coffin rhizomes are used as an expectorant, laxative, cardiotonic and diuretic.

Rhizomes contain about 1% essential oil, in its composition: asarone - 30-50% (Fig. 2), asaronic aldehyde - 2-3%, trans-isoasarone, trans-methyliso-eugenol, diazaron, SpH18O ester, sesquiterpene hydrocarbon, sesquiterpene alcohol, terpene C10H16 - 1-2%, 1-bornyl acetate - 12-13%, tricyclic sesquiterpene C15H24 - 10-12%, methyl eugenol (or methylisoeugenol) - 15-20%, asaronic acid; phenolic compounds (a-asarone). Triterpenoids: 24a-methylcholesten-5-ol-3p, 24-a-ethylcholestanol-5,22-ol-3p, 24a-ethylcholesten-5-ol-3p, 24a-ethylcholestanol-3p. Higher aliphatic alcohols: n-dodecanol, n-tetradecanol, n-hexadecanol, n-docosanol, n-tetracosanol, n-cis-octadecen-9-ol-1, 3,7,11,15-tetramethylhexadecen-1-ol- 1.

Rice. 2. Structural formula of asarone

The leaves contain steroids (sitosterol), phenol carboxylic acids (d-coumaric, caffeic, ferulic), flavonoids in the hydrolyzate (kaempferol, quercetin), flavonoids (quercetin 3-glucoside, kaempferol 3-galactoside - trifolin, kaempferol 3-ru-tinoside , quercetin), triterpenoids (cholesten-5-ol-3р, 24а-methylcholesten-5-ol-3р, 24 а-ethylcholestadien-5,22,-ol-3р, 24 а-ethylcholesten-5-ol -3р, 24-ethylcho-lestanol-3Р), higher aliphatic alcohols (n-octadecanol, n-eicosanol, n-tetracosanol, 3,7,11,15-tetramethylhexadecen-2-ol-1), higher fatty acids (n-hexadecanoic, n-octadecanoic, n-octadecene-9-ova, n-octadecadiene-9,12-ova, n-octadecatriene-9,12,15-ova).

Of the physico-chemical methods used to establish the authenticity of the analysis of leaves of the European coffin, TLC for the presence of asarone is known. The content of essential oil, with a norm of at least 0.5%, as an active group of biologically active substances, is determined according to State Fund XI. Distillation time 3 hours.

Considering the use of raw materials from the hoofed grass in allopathy and homeopathic medicine, there is a need to develop new reproducible and unified control methods to control the quality of raw materials and medicines from the European hoofed grass. On the pharmaceutical market there is a variety of herbal medicines based on the raw material of the European hoofed grass, which has found wide use in foreign medicine. The plant is official. The problems of establishing the authenticity of raw materials have been resolved, while the question of proper standardization of biologically active substances in raw materials and dosage forms remains open.

LITERATURE

Atlas of medicinal plants of Russia. - M., 2006. - P. 140-142.

Budantsev A.L., Lesiovskaya E.E. Wild growing useful plants Russia. - St. Petersburg: SPHFA, 2001. - pp. 59-60.

State Pharmacopoeia of the USSR XI edition. Vol. 1. - M.: Medicine, 1987. - P. 290.

State register of medicines. - 2001. - T. 1. - P. 223.

Nuzhny V.P., Rozhanets V.V., Efremov A.P. Medicinal plants and phytocompositions in narcology. - M.: KomKniga, 2006. - 512 p.

Plant resources of the USSR. Flowering plants, their chemical composition, use. - Leningrad: Science, 1985. - pp. 19-20.

Cherepanov S.K. Vascular plants of the USSR. - Leningrad: Science, 1981. -S. 35.

Ennet, Diether. Heilpflanzen und Drogen. - Leipzig: Bibliographisches Institut, 1990. - P. 133-134.

ASARUM EUROPEUM. CHEMICAL COMPOUNDS, PHARMACOLOGICAL PROPERTIES AND APPLICATION IN MEDICINE

N.N. Tschurevitch, A.A. Markarian

Department of pharmacy with course social pharmacy Professional education after university for pharmacist faculty Moscow I.M. Sechenov Medical Academy Trofimova str., 8, Moscow, Russia, 119991, tel. +79114636467, email: [email protected]

The purpose of this study is determined by research of chemical compounds and pharmacological properties and application in medicine by raw material of Asarum europeum and the drugs base upon the raw material. In article authors report about pharmacognostic characteristics by drug raw material of Asarum europeum; chemical compounds, which containing in different parts of the plant and possibility by application freshly gathered and desiccated raw material in medicinal and homeopathic practice.

Key words: Asarum europaeum, Azaron.

Instructions for use:

Beneficial properties of European coffin

European hooffoot is a plant from the Kirkazonaceae family with green, shiny leaves on shaggy petioles, with the same slightly shaggy stems, and a pungent, specific odor. European hooffoot blooms in April and May with bell-like flowers of a dark brown-red color.

The pharmaceutical name of the plant is coffin rhizome; popularly, the flower is also called hernia root, hare leaf, or emetic root.

In official medicine, the root of the European coffin is used to prepare medicine, and in folk medicine, both the root and fresh leaves are used.

They collect ungulates in ravines and deciduous forests.

The main purpose of the plant is to treat chronic forms of alcoholism, for which rhizomes and roots of the European ungulate are collected at the end of summer and autumn. It is believed that it is best to use fresh roots and grass for treatment. Raw materials are stored in boxes lined with paper on the inside. If there are no conditions for storing fresh roots, they can be dried at a temperature of no more than 35 degrees, but it should be borne in mind that healing properties the plants are partially lost.

Essential oils, alkaloids, asaronic acid, bornyl acetate, glycosides, coumarin, phytosterols, flavonoids, astringents, resins, organic acids, mucus, saponin were found in the rhizomes of the plant.

The use of leaves and roots of European coffin

There are two approaches to treating alcoholism with the roots of the European hoofweed: one is used when a person does not recognize his addiction, and the second when there is a conscious desire to get rid of alcoholism.

For a person who is being treated by relatives without his noticing, the following decoction is prepared: one tablespoon of the dried root of the European hoofed grass is poured with water and boiled over low heat for 5 minutes. After this, the broth is infused for one hour, filtered, and put in the refrigerator. The resulting product is added to a person’s alcohol at the rate of one tablespoon of decoction per 200 ml of vodka. The “medicine” causes a person to vomit, and the treatment itself is generally based on developing a reflex of aversion to alcohol, so you will need to add the decoction to the alcohol several more times. As practice shows, after 3-4 times, alcohol without adding hoof decoction will also cause vomiting.

If a person is being treated consciously, it is advisable that the therapy takes place under the supervision of a doctor. The same recipe can be used. You can prepare this remedy: one teaspoon of hoofed grass is mixed with two teaspoons of green walnut pericarp and one teaspoon of this mixture is poured with wine (4 liters), left for 2 weeks, and drunk 1 glass 1-2 times a day before meals. During treatment, the patient feels nausea, tightness in the sternum, is in a painful state, and may periodically begin to vomit. All these sensations force a person to give up alcohol.

It has also been established that European hooffoot has a bronchodilator, anti-inflammatory, and expectorant effect, therefore, in addition to treating alcoholism, the plant is used to treat pneumonia, bronchitis, tuberculosis, asthma, colds, diseases of the gastrointestinal tract, liver, urinary and gall bladder, and bile ducts. Hoofwood also helps in neurotic conditions, with increased excitability, migraines, insomnia, and headaches. To do this, prepare an infusion or decoction of the plant, which is diluted with hot milk or honey immediately before use.

For cooking daily norm tincture: two teaspoons of European hoofed grass, pour 250 ml of boiling water, infuse in a thermos.

Lotions with a decoction can be made for eczema caused by nervousness.

It has also been noted that a non-concentrated tincture of the leaves of the European hooffoot helps with gynecological diseases, increases the tone of the veins, accelerates blood flow, and restores normal cardiac activity.

Contraindications

It is undesirable to treat yourself with European hoof - the plant is poisonous, and exceeding the permissible dosage can lead to serious problems with the functioning of the intestines, stomach, kidneys, liver, and gall bladder.

When treating alcoholism with hoofed grass, you should not give more than two tablespoons of decoction at a time.

Asarum europaeum or European hooffoot is a famous plant used in herbal medicine. The main direction of its use is the treatment of alcohol dependence. The plant received this property due to its active composition. Find out how the herb coffin is used and prepared for alcoholism, how to use the components correctly, and what they can be used for additionally.

What is hoofed grass

A perennial evergreen herbaceous plant with a creeping cord-like rhizome and a creeping branching stem. It belongs to the family Kirkazonaceae (lat. Aristolochiaceae), the species of the genus is classified as Azarum (lat. Asarum). The plant is popular among healers and healers, which explains the additional common names: hare root, emetic root, emetic, wild pepper, earthen incense, undergrowth, core.

The peculiar shape of the leaf led to another name - hoof. It has a solid surface and long actinomorphic petioles. The flowers have a three-membered corolla-shaped perianth (simple), bell-shaped. The perianth remains with the fruit. The flower has 12 stamens, the pistil has a lower six-locular ovary and a short style. The fruit is presented in a capsule. In the Russian Federation it grows in the forest-steppe and forest zones of the European zone, in the southern part of Western Siberia. Distributed in broad-leaved, coniferous and coniferous-deciduous shady forests, poisonous.

Compound

Due to its composition, rich in valuable substances, the raw materials of the cleft wolf plant are used for the manufacture of pharmaceuticals in many European countries(Poland, Sweden, Germany, the Netherlands). The plant includes the following elements and compounds of medical interest:

• tannins, bitter substances, glycosides;
• diazoron, asarone, bornyl acetate, 1-pinene;
• asaryldehyde;
• methyl eugenol, azarin alkaloid, eugenol;
• tannins, bactericidal substances;
• eugenol, kaempferol;
• essential oils;
• mineral salts of calcium, potassium, quercetin;
• silicalcite, resins, starch, mucus, sugar;
• coumarin, flavonoids;
• organic acids.

Beneficial features

Cardiac glycosides, kirkazonic acids, tannins (resinous and tannins), flavonoids provide choleretic and diuretic properties, adrenaline-like, emetic and laxative effects, antipyretic and sedative effects of the drug. Galenic components from rhizomes are used as an expectorant, diuretic, and emetic. The plant has anti-inflammatory, hemostatic, bronchodilator, anthelmintic, anti-sclerotic, lactic and wound-healing effects.

An infusion of leaves is used for diseases of the stomach, kidneys and liver. A decoction of them is drunk for heart disease, alcohol addiction, mushroom poisoning, emotional instability, headaches, as a diuretic, and for jaundice. A decoction of the roots and rhizomes of the plant is used as a diuretic for kidney diseases. A decoction of grape syrup enhances potency.

Dried and ground to a powder, the roots and rhizomes of the hoof are used to treat the common cold. The effect is achieved due to the bactericidal substances contained in the plant. It is recommended to apply fresh and pre-crushed leaves of the coffin to abscesses, and a tincture of the leaves in vinegar can be used to wipe areas of the skin affected by scabies. Rubbing with a decoction helps with infectious eye diseases. Essential oils of the plant have a pleasant smell, so their use after the necessary processing is permissible in perfumery.

Application

The pharmaceutical market presents a good choice herbal medicines that contain raw materials from herbs that are widely used in domestic and foreign medicine. Coffin is one of the plants officially recognized by pharmaceuticals. Herbalists and traditional medicine healers use European hooffoot for alcoholism, but in addition, the plant can be used in the treatment of the following diseases:

In pharmacies you can find dried roots and herbs; blyakotnik is included in some drugs, for example, drops for alcoholism or the herbal mixture “Stopal”. A tincture from the leaves of the plant is part of the “Akofit” remedy, used for neuritis and radiculitis. It is advisable to use the product under the supervision of a doctor and with permission, because the plant is very poisonous. Uncontrolled use can lead to severe poisoning. It is recommended to strictly adhere to the dosage and not exceed it.

Herb hoofed grass for alcoholism

Hoofweed has been used for alcoholism for a long time. The effectiveness is due to the fact that ingestion of a decoction of the roots along with alcohol produces a reaction of nausea and vomiting. This causes an aversion to alcoholic beverages, and the person stops abusing them. The following recipes will help cope with addiction:

1. Brew a tablespoon of raw material with a glass of boiling water, boil in a water bath for half an hour, strain. Bring the volume back to the original volume. Take two tablespoons three times a day after meals - one tablespoon per glass of vodka. This causes vomiting and a persistent aversion to alcohol.
2. Mix 20 g of coffin leaves and 40 g of green fruit peel walnut, pour a teaspoon of the mixture with a glass of wine. Insist for half an hour, drink. You should consume 4 liters of plant infusion per month. This will create an aversion to drinking alcohol.

Poisonous herbaceous medicinal plant!

European hoofweed is a medicinal plant and is widely used in folk medicine in the treatment of diseases, effective remedy in the treatment of alcoholism.

Latin name: Asarum europaeum.

English names: asarabacca, European wild ginger, hazelwort, or wild spikenard.

Family: Kirkazonaceae - Aristolochiaceae.

Synonym: Common hoofweed.

Common names: hernia, emetic root, hare leaf.

Pharmacy name: rhizome of the hoofed coffin - Asari rhizoma.

Parts used: roots, rhizomes, leaves.

European hoofweed - photo, description of the medicinal plant

Botanical description: European hoofweed is a perennial self-pollinating plant with creeping roots and stems. As it grows, the stem branches and takes root, forming significant patches in deciduous and mixed forests. The name European is due to the distribution of this species throughout Europe.

The rhizome of the plant reaches 50 cm. The entire plant is covered with short hairs. The leaves are long-petiolate, heart-shaped at the base, dark green, shiny above and light below. The ungulate blooms in April-May in the 3rd or even 8th year of life. Its small single drooping bell-shaped burgundy-whitish or red-brown flowers are not always noticeable, since they lie on the soil, covered with leaves. But the six-celled capsules, which ripen in June, drop triangular-ovoid seeds directly onto the soil, which are carried throughout the forest by ants.

European hoofed grass has a peculiar bitter taste and spicy smell. When you rub a fresh plant, the smell intensifies.

Habitat: grows everywhere in Europe.

Collection and preparation. The leaves and roots of European hoofed grass are used as medicinal raw materials. The roots of the plant are dug up in spring or autumn. They are washed with cool water, cut into small pieces and dried in an oven or oven.

Clefthoof leaves are collected during the flowering period of the grass: in April, May and until mid-June, although traditional healers believe that the leaves can be harvested almost all summer. Dry the product in a warm place, avoiding direct contact sun rays, in a well-ventilated area at a temperature not exceeding fifty degrees.

The plant is stored for three years in wooden boxes, pre-lined with paper. This plant is poisonous, so precautions must be taken when collecting and preparing it.

Chemical composition. Clefthoof leaves contain asarone, a camphor-type substance. IN essential oil, isolated from the plant, also contain pinene, eugenol and borniolacetate.

The use of hoofweed in folk medicine

Traditional medicine uses the roots of the plant along with the leaves in the form of an aqueous or milky decoction as a diuretic, improves digestion, anthelmintic, and is used as folk remedy in the treatment of alcoholism, heart disease, women's diseases, and in large quantities an emetic. Milk removes bitterness and neutralizes the poison of the roots. Therefore, milk decoctions are more popular. They have a regulating effect during menopause and irregular periods.

A decoction of the leaves and rhizomes of the coffin is used in the form of lotions for eczema of a nervous nature and headaches. European hoofed grass is also used in mixtures with other herbs for jaundice and bronchitis.

European hooffoot is an effective folk remedy for alcoholism, a decoction of the roots of which is added to vodka. Due to their toxicity and ability to induce vomiting, this mixture is designed to induce severe nausea and alcohol withdrawal.

ATTENTION! The plant is poisonous, use in strict dosages, as directed and under the supervision of a doctor!

Treatment with European hoof

European hoofweed - a folk remedy for treating alcoholism

1. Alcoholism. Treatment for alcoholism with a hoof will be more effective if it is carried out without the knowledge of the patient.
   In 200 ml of water and add 1 teaspoon of crushed plant roots, boil for 10 minutes; leave for 30 minutes in a warm place, strain and place in the refrigerator.
   Add directly to alcohol or food. First, 1 tablespoon, if the effect is weak, you need to gradually increase the dosage. You cannot add more than 2 tablespoons at a time.
2. Arrhythmia is atrial fibrillation. Pour 1/2 teaspoon of chopped root into 200 ml of boiling water. Wrap, leave for 1 hour, strain and top up to the original volume. Drink 1 tablespoon as a sedative.
3. Parkinson's disease. 1 tablespoon of crushed leaves pour 500 ml sunflower oil, leave for 2 weeks in the sun or in a warm place. Use to rub the spine several times a day for 5 minutes.
4. Helminthiasis. Take a decoction of 1/5 teaspoon of crushed leaves of the European hoofed grass in 200 ml of boiling water. During treatment, drink 1 tablespoon of decoction 2 times a day.
5. Arterial hypotension. Pour 200 ml of boiling water over 1 gram of leaves, cover and leave for 1 hour. Drink 1 tablespoon 15 minutes before meals. Strictly dose!
6. Dyspepsia(indigestion). Pour 1/2 teaspoon of crushed root into 200 ml of boiling water (or goat milk), heat in a boiling water bath for 1 minute, strain and top up to the original volume. Drink 1 tablespoon before meals.
7. Myocardial infarction. 1/2 tsp. crushed root, pour 200 ml of boiling water (or goat's milk, heat in a boiling water bath for 15 minutes. Strain and add to the original volume. Drink 1 tablespoon before meals as a sedative.
8. Conjunctivitis. Pour 2 grams of crushed root into 200 ml of boiled water, heat in a boiling water bath for 30 minutes, remove from heat and leave for 10 minutes. Strain. Rinse your eyes with the decoction in the morning and evening.
9. Metrorrhagia(uterine bleeding). Drink with milk once a day, on an empty stomach, 0.2-0.5 g of plant root powder.
10. Migraine. Take the powdered root on the tip of a folding knife (0.2-0.5 grams), pour it into a glass of milk and drink it on an empty stomach in the morning.
11. Myocarditis(inflammation of the heart muscle). Pour 1/2 teaspoon of crushed European coffin root into 200 ml of boiling water in a thermos, leave for 1 hour. Strain and top up to original volume. Store the infusion in a thermos for no more than 24 hours. Drink 1 tablespoon as a sedative.
12. Cholangitis, cholelithiasis. An aqueous infusion of coffin leaves with the addition of inflorescences in equal parts. Dosage: 1 tablespoon of crushed plant mixture per 200 ml of boiling water.
13. Enteritis, acute enterocolitis. Pour 1/2 teaspoon of crushed European hoofed root root into 200 ml of boiling water (or goat’s milk), heat in a boiling water bath for 1 minute. Strain and top up to original volume. Drink 1 tablespoon before meals.

Contraindications. The roots of the plant are poisonous, do not abuse them. In case of overdose, internal organs are affected gastrointestinal tract. The plant is contraindicated in heart failure.